Recombinant Human CD-7

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Recombinant Human CD-7

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Cat. No. : CDA079P
Product Overview : Recombinant Human full length CD-7 protein expressed in E.coli,66 kDa.
Description : CD7 (gp40, Leu9) is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on maligant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3"-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylat
Source : E.coli.
Presentation : Recombinant Human CD-7 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Applications : •ELISA•Inhibition Assays •Western Blotting
Characterization : On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 66 kDa.
Storage : Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Synonyms : CD7; GP40; LEU-9; TP41; Tp40; GP40; LEU-9; Leu-9; CD7 antigen; CD7 antigen (p41); CD7 molecule; T-cell antigen CD7; T-cell leukemia antigen; p41 protein.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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