Recombinant Human HDAC2, His-tagged

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Recombinant Human HDAC2, His-tagged

HDAC2 Related Products

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Cat. No. : HDAC2-3565H
Product Overview : Recombinant human HDAC2 protein, fused to His-tag at C-terminus, was expressed in high-5 cells using baculovirus expression system and purified by using conventional chromatography techniques (1-488aa).
Description : HDAC2 belongs to the histone deacetylase family that act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones. It forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. It also plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Form : Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT, 0.1mM PMSF
Molecular Mass : 56.4 kDa (496aa)
Purity : > 85 % by SDS-PAGE
Concentration : 0.25 mg/ml (determined by Bradford assay )
Sequences of amino acids : MAYSQGGGKK KVCYYYDGDI GNYYYGQGHP MKPHRIRMTH NLLLNYGLYR KMEIYRPHKA TAEEMTKYHS DEYIKFLRSI RPDNMSEYSK QMQRFNVGED CPVFDGLFEF CQLSTGGSVA GAVKLNRQQT DMAVNWAGGL HHAKKSEASG FCYVNDIVLA ILELLKYHQR VLYIDIDIHH GDGVEEAFYT TDRVMTVSFH KYGEYFPGTG DLRDIGAGKG KYYAVNFPMR DGIDDESYGQ IFKPIISKVM EMYQPSAVVL QCGADSLSGD RLGCFNLTVK GHAKCVEVVK TFNLPLLMLG GGGYTIRNVA RCWTYETAVA LDCEIPNELP YNDYFEYFGP DFKLHISPSN MTNQNTPEYM EKIKQRLFEN LRMLPHAPGV QMQAIPEDAV HEDSGDEDGE DPDKRISIRA SDKRIACDEE FSDSEDEGEG GRRNVADHKK GAKKARIEED KKETEDKKTD VKEEDKSKDN SGEKTDTKGT KSEQLSNPSR HHHHHH
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°Cor -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : HDAC2 histone deacetylase 2 [ Homo sapiens ]
Official Symbol : HDAC2
Synonyms : HDAC2; RPD3; YAF1; histone deacetylase 2; Histone deacetylase 2; OTTHUMP00000017046; YY1-associated factor 1; transcriptional regulator homolog RPD3; EC 3.5.1.98; HD2
Gene ID : 3066
mRNA Refseq : NM_001527
Protein Refseq : NP_001518
MIM : 605164
UniProt ID : Q92769
Chromosome Location : 6q21
Function : enzyme binding; histone deacetylase activity; hydrolase activity; specific transcriptional repressor activity; transcription activator activity; transcription factor activity; transcription factor binding

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