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Recombinant Mouse Interleukin 28B, His-tag, MBP-tag

Cat. No.: IL28B-214M
Product Overview: Recombinant Mouse Interleukin 28B has the matured 174 aa at its C terminal, His tag and MBP tag at the N terminal. It is expressed and purified from an E.coli system.
Description: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Source: E. coli
Molecular Mass: 63.3 kD
Formulation: 20 mM Tris-Cl (pH 7.9) 20% Glycerol, 100 mM KCl, 1 mM DTT and 0.2 mM EDTA
Purity: >95% based on SDS-PAGE analysis
Concentration: 500 µg/ml
Reconsitution: Already in liquid form.
Storage: -80 °C
Shipping Conditions: Dry Ice
OfficialSymbol: Il28b
Gene Name: Il28b interleukin 28B [ Mus musculus ]
Synonyms: Il28b; interleukin 28B; Il28; IFL-1; INF-alpha; IL-28B INF-lambda; interleukin 28; interferon alpha; IFNL3; IL28C; interleukin-28B; IFN-lambda-3; interferon lambda-3
Gene ID: 338374
mRNA Refseq: NM_177396
Protein Refseq: NP_796370
UniProt ID: Q8CGK6
Chromosome Location: 7 A3; 7
Pathway: Jak-STAT signaling pathway
Function: cytokine activity; receptor binding

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