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Active Recombinant Human MGAT5 protein, His-tagged

Cat.No. : MGAT5-1120H
Product Overview : Recombinant Human MGAT5 protein(NP_002401.1)(Leu189-Leu741), fused with His tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Bio-activity : Measured by its ability to transfer N-Acetyl-α-D-glucosamine from UDP-N-Acetyl-α-D-glucosamine to a biantennary N-linked core pentasaccharide in a CD39L3 coupled assay. The specific activity is >10pmoles/min/μg
Molecular Mass : The recombinant human MGAT5 consists of 564 amino acids and predictes a molecular mass of 65 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh MGAT5 is approximately 60-65 kDa.
Protein Length : Leu189-Leu741
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [ Homo sapiens ]
Official Symbol : MGAT5
Synonyms : MGAT5; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase; alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; GNT V; glcNAc-T V; N-acetylglucosaminyl-transferase V; mannoside acetylglucosaminyltransferase 5; alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; GNT-V; GNT-VA; FLJ31899; FLJ43217; DKFZp686B24166;
Gene ID : 4249
mRNA Refseq : NM_002410
Protein Refseq : NP_002401
MIM : 601774
UniProt ID : Q09328

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What role does MGAT5 play in immune responses? 07/24/2022

MGAT5 modulates immune responses.

What is the primary role of MGAT5 in glycoprotein synthesis? 12/24/2021

MGAT5 is key for glycoprotein glycosylation.

How does MGAT5 contribute to cell signaling and communication? 09/09/2021

It affects cell signaling by altering glycosylation patterns.

What is the impact of altered MGAT5 activity on cancer progression? 09/06/2021

Altered MGAT5 activity is linked to cancer progression.

How do genetic variations in MGAT5 affect cellular functions? 03/22/2020

Genetic changes in MGAT5 impact glycosylation and cell processes.

What potential therapeutic applications arise from targeting MGAT5 in diseases? 01/29/2020

Targeting MGAT5 could treat diseases involving abnormal glycosylation.

How does MGAT5 interact with other enzymes in glycosylation pathways? 06/08/2019

MGAT5 collaborates with other enzymes in glycosylation.

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02/19/2023

    Trusted for research integrity, a dependable research collaborator.

    10/07/2020

      Efficient service, accelerates research progress.

      11/24/2018

        Outstanding accuracy, an essential part of our research.

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