Recombinant Human Peroxiredoxin 2, His-tagged PRDX2-1438H

Recombinant Human Peroxiredoxin 2, His-tagged

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Recombinant Human Peroxiredoxin 2, His-tagged

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Cat. No. : PRDX2-1438H
Product Overview : PRDX2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 198 amino acids and having a molecular mass of 21.8 kDa. The PRDX2 is purified by proprietary chromatographic techniques.
Description : PRDX2 is part of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. PRDX2 takes part as an antioxidant protective role in cells. T-cells. PRDX2 has proliferative effect in cancer development or progression. If PRDX2 protection is insufficient against peroxidases, the DNA damage results in neurological disease such as Alzheimer"s or DNA damage leading to cancer.
Source : Human
Host : Escherichia Coli.
Form : The Peroxiredoxin solution contains 20 mM Tris-HCl pH-8, & 10% glycerol.
Purity : Greater than 90.0% as determined by SDS-PAGE.
Bio-activity : The specific activity was found to be approximately 200-230 pmole/min/µg. The enzymatic activity was confirmed by measuring the remaining peroxide after incubation of PRDX2 and peroxide for 20 min at room temperature. Specific activity is defined as the amount of hydroperoxide that 1 ug of enzyme can reduce at 25°C for 1 minute.
Physical Appearance : Sterile Filtered colorless solution.
Amino acid sequence : MASGNARIGK PAPDFKATAV VDGAFKEVKL SDYKGKYVVL FFYPLDFTFV CPTEIIAFSN RAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTRR LSEDYGVLKT DEGIAYRGLF IIDGKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS DTIKPNVDDS KEYFSKHN
Storage : PRDX2 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
PDB rendering basedon 1qmv :

Gene Name : PRDX2 peroxiredoxin 2 [ Homo sapiens ]
Official Symbol : PRDX2
Synonyms : PRDX2; peroxiredoxin 2; PRP; TSA; PRX2; TPX1; NKEFB; PRXII; TDPX1; MGC4104; peroxiredoxin-2; torin; NKEF-B; OTTHUMP00000165823; OTTHUMP00000165825; thioredoxin peroxidase 1; thiol-specific antioxidant 1; natural killer-enhancing factor B; thiol-specific antioxidant protein ;natural killer cell-enhancing factor B; thioredoxin-dependent peroxide reductase 1
Gene ID : 7001
mRNA Refseq : NM_005809
Protein Refseq : NP_005800
MIM : 600538
UniProt ID : P32119
Chromosome Location : 19p13
Pathway : Selenium Pathway
Function : antioxidant activity; oxidoreductase activity; thioredoxin peroxidase activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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