| Cat. No. : |
NTF3-012H |
| Product Overview : |
Human NTF3 (P20783) full-elngth recombinant protein expressed in Escherichia coli. |
| Description : |
Neurotrophin-3 is a protein that in humans is encoded by the NTF3 gene. The protein encoded by this gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins. It is a protein growth factor which has activity on certain neurons of the peripheral and central nervous system; it helps to support the survival and differentiation of existing neurons, and encourages the growth and differentiation of new neurons and synapses. NT-3 was the third neurotrophic factor to be characterized, after nerve growth factor (NGF) and BDNF. |
| Theoretical MW (kDa) : |
13.6 |
| Form : |
Lyophilized |
| Preparation Method : |
Escherichia coli expression system |
| Purity : |
μ 98% by SDS-PAGE, μ 98% by HPLC |
| Endotoxin Level : |
< 0.1 ng/ug |
| Activity : |
The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/mL. |
| Application : |
SDS-PAGE |
| Storage : |
Store at -20°C on dry atmosphere.After reconstitution with deionized water, store at -20°C.Aliquot to avoid repeated freezing and thawing. |
| Unitprot ID : |
P20783 |
| Pathways : |
Neurotrophin signaling pathway; MAPK signaling pathway |
| PDB rendering basedon 1b8k. : |
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