Recombinant Human NTF3(full-length) NTF3-012H

Recombinant Human NTF3(full-length)

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Recombinant Human NTF3(full-length)

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Cat. No. : NTF3-012H
Product Overview : Human NTF3 (P20783) full-elngth recombinant protein expressed in Escherichia coli.
Description : Neurotrophin-3 is a protein that in humans is encoded by the NTF3 gene. The protein encoded by this gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins. It is a protein growth factor which has activity on certain neurons of the peripheral and central nervous system; it helps to support the survival and differentiation of existing neurons, and encourages the growth and differentiation of new neurons and synapses. NT-3 was the third neurotrophic factor to be characterized, after nerve growth factor (NGF) and BDNF.
Theoretical MW (kDa) : 13.6
Form : Lyophilized
Preparation Method : Escherichia coli expression system
Purity : μ 98% by SDS-PAGE, μ 98% by HPLC
Endotoxin Level : < 0.1 ng/ug
Activity : The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/mL.
Application : SDS-PAGE
Storage : Store at -20°C on dry atmosphere.After reconstitution with deionized water, store at -20°C.Aliquot to avoid repeated freezing and thawing.
Unitprot ID : P20783
Pathways : Neurotrophin signaling pathway; MAPK signaling pathway
PDB rendering basedon 1b8k. :

Gene Name : NTF3 neurotrophin 3 [ Homo sapiens ]
Official Symbol : NTF3
Synonyms : NTF3; neurotrophin 3; NT3; HDNF; NGF2; NGF-2; MGC129711; neurotrophin-3; NT-3; OTTHUMP00000239132; OTTHUMP00000239133; neurotrophic factor; nerve growth factor 2; NGF-2; NGF2
Gene ID : 4908
mRNA Refseq : NM_001102654
Protein Refseq : NP_001096124
MIM : 162660
Chromosome Location : 12p13
Function : growth factor activity; nerve growth factor binding; neurotrophin receptor binding

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