Recombinant Human NTF3(full-length)
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| Cat. No. : | NTF3-012H |
| Product Overview : | Human NTF3 (P20783) full-elngth recombinant protein expressed in Escherichia coli. |
| Description : | Neurotrophin-3 is a protein that in humans is encoded by the NTF3 gene. The protein encoded by this gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins. It is a protein growth factor which has activity on certain neurons of the peripheral and central nervous system; it helps to support the survival and differentiation of existing neurons, and encourages the growth and differentiation of new neurons and synapses. NT-3 was the third neurotrophic factor to be characterized, after nerve growth factor (NGF) and BDNF. |
| Theoretical MW (kDa) : | 13.6 |
| Form : | Lyophilized |
| Preparation Method : | Escherichia coli expression system |
| Purity : | μ 98% by SDS-PAGE, μ 98% by HPLC |
| Endotoxin Level : | < 0.1 ng/ug |
| Activity : | The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/mL. |
| Application : | SDS-PAGE |
| Storage : | Store at -20°C on dry atmosphere.After reconstitution with deionized water, store at -20°C.Aliquot to avoid repeated freezing and thawing. |
| Unitprot ID : | P20783 |
| Pathways : | Neurotrophin signaling pathway; MAPK signaling pathway |
| PDB rendering basedon 1b8k. : |
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| Gene Name : | NTF3 neurotrophin 3 [ Homo sapiens ] |
| Official Symbol : | NTF3 |
| Synonyms : | NTF3; neurotrophin 3; NT3; HDNF; NGF2; NGF-2; MGC129711; neurotrophin-3; NT-3; OTTHUMP00000239132; OTTHUMP00000239133; neurotrophic factor; nerve growth factor 2; NGF-2; NGF2 |
| Gene ID : | 4908 |
| mRNA Refseq : | NM_001102654 |
| Protein Refseq : | NP_001096124 |
| MIM : | 162660 |
| Chromosome Location : | 12p13 |
| Function : | growth factor activity; nerve growth factor binding; neurotrophin receptor binding |
◆ Recombinant Protein
| NTF3-3621H | Recombinant Human Neurotrophin 3 | +Inquiry |
| NTF3-044H | Recombinant Human Neurotrophin 3 | +Inquiry |
| NTF3-011H | Recombinant Human NTF3(139-257aa) | +Inquiry |
| Ntf3-018M | Recombinant Mouse Neurotrophin 3 | +Inquiry |
| NTF3-128H | Recombinant Human 3 -Nucleotidase | +Inquiry |
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◆ Native Protein
| NTF3-29249TH | Native Human NTF3 | +Inquiry |
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◆ Lysates
| NTF3-3670HCL | Recombinant Human NTF3 293 Cell Lysate | +Inquiry |
| NTF3-3671HCL | Recombinant Human NTF3 293 Cell Lysate | +Inquiry |
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