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Recombinant Mouse Fgf15, His-tagged

Cat.No. : Fgf15-499M
Product Overview : Total 203 AA. MW: 23.78 kDa (calculated). N-Terminal His-tag, 10 extra AA (highlighted).
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  • Gene Information
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Cat. No. : Fgf15-499M
Description : Fibroblast growth factor 19 is a protein that in humans is encoded by the FGF19 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development.
Source : E. coli
Species : Mouse
Form : Filtered (0,4 μm) and lyophilized in 0.5 mg/mL in 20mM TRIS, 20mM NaCl, PH 8.0.
Research topic : Energy metabolism and body weight regulation
Purity : >90%
Reconstitution : Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Applications : ELISA, Western blotting
Quality Control Test : BCA to determine quantity of the protein; SDS PAGE to determine purity of the protein; LAL to determine quantity of endotoxin
Sequences of amino acids : MKHHHHHHAS RPLAQQSQSV SDEDPLFLYG WGKITRLQYL YSAGPYVSNC FLRIRSDGSV DCEEDQNERN LLEFRAVALK TIAIKDVSSV RYLCMSADGK IYGLIRYSEE DCTFREEMDC LGYNQYRSMK HHLHIIFIQA KPREQLQDQK PSNFIPVFHR SFFETGDQLR SKMFSLPLES DSMDPFRMVE DVDHLVKSPS FQK
Storage : Store lyophilized protein at -20°C. Lyophilized protein remains stable until the expiry date when stored at -20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after one week at 4°C.
Gene Name : Fgf15 fibroblast growth factor 15 [ Mus musculus ]
Official Symbol : Fgf15
Synonyms : Fgf15; fibroblast growth factor 15; FGF19; FGF-15
Gene ID : 14170
mRNA Refseq : NM_008003
Protein Refseq : NP_032029
Pathway : Downstream signaling of activated FGFR; ESC Pluripotency Pathways; FGFR ligand binding and activation; FGFR1 ligand binding and activation; FGFR1b ligand binding and activation; FGFR1c and Klotho ligand binding and activation; FGFR2b ligand binding and activation; FRS2-mediated cascade; IRS-related events; MAPK signaling pathway; PI-3K cascade; Pathways in cancer; Regulation of actin cytoskeleton; Signaling by FGFR; Signaling by Insulin receptor; Insulin receptor signalling cascade
Function : fibroblast growth factor receptor binding; growth factor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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