Human Transferrin

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Human Transferrin

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Cat. No. : TF-4778H
Product Overview : This product is excellent for use as a growth factor for primary, continuous, and transformed cell lines.
Description : TF is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h). TF has a molecular weight of around 80 kDa and contains 2 specific high-affinity Fe (III) binding sites.
Source : Human Plasma
Species : Human
Source Testing : The normal human serum/plasma of each donor unit, from which this product was manufactured, has been tested and certified negative for the following by FDA approved testing procedures: HBsAg, Anti-HCV, Anti-HIV-1, Anti-HIV-2, Syphilis, ALT Test and NAT-PCR ( HAV, HIV, HBC, HCV and Parovirus B19). Human blood products should always be treated in accordance with universal handling precautions.
Protein : 97.0% By Lowry.
Purity : > 98% By Cellulose Acetate Electrophoresis.
Iron : 1500 µg/g By Diagnostic Assay.
pH : 7.06 (3% Solution)
Endotoxin : < 0.076 EU/mg By LAL.
Sodium : 0.0-10.0 mg/g By Flame Photometer.
Chloride : 0.0-12.0 mg/g By Coulometric Titrator.
Moisture : 0.87% By Karl Fisher.
Storage : Store at -20°C.
Pathways : EPHB forward signaling; Formation of Platelet plug; HIF-1-alpha transcription factor network; Hemostasis; Iron uptake and transport; Mineral absorption; Platelet Activation; Platelet degranulation; Response to elevated platelet cytosolic Ca2+; Transferrin endocytosis and recycling; Transmembrane transport of small molecules
PDBrendering based on 1a8e :

Gene Name : TF transferrin [ Homo sapiens ]
Official Symbol : TF
Synonyms : TF; transferring; PRO1557; PRO2086; DKFZp781D0156; serotransferrin; siderophilin; OTTHUMP00000197155; beta-1 metal-binding globulin; Serotransferrin; Beta-1 metal-binding globulin; Siderophilin
Gene ID : 7018
mRNA Refseq : NM_001063
Protein Refseq : NP_001054
MIM : 190000
UniProt ID : P02787
Chromosome Location : 3q21
Function : ferric iron binding; metal ion binding; protein binding; ubiquitin protein ligase binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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