Human Transferrin
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Cat. No. : | TF-4778H |
Product Overview : | This product is excellent for use as a growth factor for primary, continuous, and transformed cell lines. |
Description : | TF is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h). TF has a molecular weight of around 80 kDa and contains 2 specific high-affinity Fe (III) binding sites. |
Source : | Human Plasma |
Species : | Human |
Source Testing : | The normal human serum/plasma of each donor unit, from which this product was manufactured, has been tested and certified negative for the following by FDA approved testing procedures: HBsAg, Anti-HCV, Anti-HIV-1, Anti-HIV-2, Syphilis, ALT Test and NAT-PCR ( HAV, HIV, HBC, HCV and Parovirus B19). Human blood products should always be treated in accordance with universal handling precautions. |
Protein : | 97.0% By Lowry. |
Purity : | > 98% By Cellulose Acetate Electrophoresis. |
Iron : | 1500 µg/g By Diagnostic Assay. |
pH : | 7.06 (3% Solution) |
Endotoxin : | < 0.076 EU/mg By LAL. |
Sodium : | 0.0-10.0 mg/g By Flame Photometer. |
Chloride : | 0.0-12.0 mg/g By Coulometric Titrator. |
Moisture : | 0.87% By Karl Fisher. |
Storage : | Store at -20°C. |
Pathways : | EPHB forward signaling; Formation of Platelet plug; HIF-1-alpha transcription factor network; Hemostasis; Iron uptake and transport; Mineral absorption; Platelet Activation; Platelet degranulation; Response to elevated platelet cytosolic Ca2+; Transferrin endocytosis and recycling; Transmembrane transport of small molecules |
PDBrendering based on 1a8e : |
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Gene Name : | TF transferrin [ Homo sapiens ] |
Official Symbol : | TF |
Synonyms : | TF; transferring; PRO1557; PRO2086; DKFZp781D0156; serotransferrin; siderophilin; OTTHUMP00000197155; beta-1 metal-binding globulin; Serotransferrin; Beta-1 metal-binding globulin; Siderophilin |
Gene ID : | 7018 |
mRNA Refseq : | NM_001063 |
Protein Refseq : | NP_001054 |
MIM : | 190000 |
UniProt ID : | P02787 |
Chromosome Location : | 3q21 |
Function : | ferric iron binding; metal ion binding; protein binding; ubiquitin protein ligase binding |
◆ Recombinant Protein
TF-651H | Recombinant Human TF Protein, MYC/DDK-tagged | +Inquiry |
TF-147H | Recombinant Human TF Protein, His-tagged | +Inquiry |
TF-146B | Recombinant Bovine TF Protein, His-tagged | +Inquiry |
Tf-151R | Recombinant Rat Tf Protein, His-tagged | +Inquiry |
TF-150P | Recombinant Pig TF Protein, His-tagged | +Inquiry |
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◆ Native Protein
TF-8271H | Native Human Serum Transferrin APO (Iron Free) | +Inquiry |
TF-93R | Native Rat Transferrin | +Inquiry |
TF-136C | Native Chicken Ovotransferrin | +Inquiry |
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◆ Lysates
TF-1208MCL | Recombinant Mouse TF cell lysate | +Inquiry |
TF-1554SCL | Recombinant Sus scrofa (Pig) TF cell lysate | +Inquiry |
TF-2542HCL | Recombinant Human TF cell lysate | +Inquiry |
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◆ Assay kits
Kit-0813 | TF (Human) Chromogenic Activity Assay Kit | +Inquiry |
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