| Cat. No. : |
TF-4778H |
| Product Overview : |
This product is excellent for use as a growth factor for primary, continuous, and transformed cell lines. |
| Description : |
TF is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h). TF has a molecular weight of around 80 kDa and contains 2 specific high-affinity Fe (III) binding sites. |
| Source : |
Human Plasma |
| Species : |
Human |
| Source Testing : |
The normal human serum/plasma of each donor unit, from which this product was manufactured, has been tested and certified negative for the following by FDA approved testing procedures: HBsAg, Anti-HCV, Anti-HIV-1, Anti-HIV-2, Syphilis, ALT Test and NAT-PCR ( HAV, HIV, HBC, HCV and Parovirus B19). Human blood products should always be treated in accordance with universal handling precautions. |
| Protein : |
97.0% By Lowry. |
| Purity : |
> 98% By Cellulose Acetate Electrophoresis. |
| Iron : |
1500 µg/g By Diagnostic Assay. |
| pH : |
7.06 (3% Solution) |
| Endotoxin : |
< 0.076 EU/mg By LAL. |
| Sodium : |
0.0-10.0 mg/g By Flame Photometer. |
| Chloride : |
0.0-12.0 mg/g By Coulometric Titrator. |
| Moisture : |
0.87% By Karl Fisher. |
| Storage : |
Store at -20°C. |
| Pathways : |
EPHB forward signaling; Formation of Platelet plug; HIF-1-alpha transcription factor network; Hemostasis; Iron uptake and transport; Mineral absorption; Platelet Activation; Platelet degranulation; Response to elevated platelet cytosolic Ca2+; Transferrin endocytosis and recycling; Transmembrane transport of small molecules |
| PDBrendering based on 1a8e : |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.