Active Recombinant Human Aminoacyl TRNA Synthetase Complex-Interacting Multifunctional Protein 1
Cat.No. : | AIMP1-338H |
Product Overview : | Recombinant human AIMP1 protein was expressed in E. coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | AIMP1-338H |
Description : | EMAP-II is a tumor derived cytokine that exerts a wide range of activities on endothelial cells, monocytes and neutrophils. EMAP-II inhibits endothelial cell proliferation, vasculogenesis, neovessel formation, and can induce apoptosis. It is also chemotactic towards neutrophils and monocytes and induces myeloperoxidase activity from neutrophils. Of clinical importance, EMAP-II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues. Mature EMAP-II is an 18.3 kDa protein, which is synthesized as the C-terminal portion of a biologically inactive precursor protein containing a propeptide of 146 amino acid residues. |
Source : | Human |
Host : | E.coli |
Form : | Supplied as a lyophilized powder. |
Purity : | >98% pure by SDS PAGE and HPLC |
Sequence : | Region of EMAP II protein corresponding to amino acids SKPIDVSRLD LRIGCIITAR KHPDADSLYV EEVDVGEIAP RTVVSGLVNH VPLEQMQNRM VILLCNLKPA KMRGVLSQAM VMCASSPEKI EILAPPNGSV PGDRITFDAF PGEPDKELNP KKKIWEQIQP DLHTNDECVA TYKGVPFEVK GKGVCRAQTM SNSGIK. |
Molecular Mass : | 18.3 kDa |
Applications : | Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
Endotoxin Levels : | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
Bioactivity : | Determined by the apoptotic effect on MCF-7 cells using a concentration of 20-40 ng/ml. |
Storage : | Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Gene Name : | AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 [ Homo sapiens ] |
Official Symbol : | AIMP1 |
Synonyms : | AIMP1; SCYE1; EMAP II; EMAP-2; EMAP-II; EMAP2; EMAPII; p43; small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating); small inducible cytokine subfamily E, member 1; OTTHUMP00000161878; ARS-interacting multifunctional protein 1; endothelial monocyte-activating polypeptide 2; endothelial-monocyte activating polypeptide II; multisynthetase complex auxiliary component p43 |
Gene ID : | 9255 |
mRNA Refseq : | NM_001142415 |
Protein Refseq : | NP_001135887 |
MIM : | 603605 |
UniProt ID : | Q12904 |
Chromosome Location : | 4q2 |
Pathway : | Cytosolic tRNA aminoacylation; Gene Expression; tRNA Aminoacylation |
Function : | cell surface binding; cytokine activity; protein binding; protein homodimerization activity; tRNA binding. |
Products Types
◆ Recombinant Protein | ||
AIMP1-130A | Active Recombinant Human AIMP1 Protein (166 aa) | +Inquiry |
AIMP1-0444H | Recombinant Human AIMP1 Protein (Lys148-Lys312), N-His-tagged | +Inquiry |
AIMP1-87H | Recombinant Human AIMP1 protein | +Inquiry |
Aimp1-7399M | Recombinant Mouse Aimp1 protein | +Inquiry |
AIMP1-865G | Recombinant Human Aminoacyl tRNA Synthetase Complex-interacting Multifunctional Protein 1, His-tagged | +Inquiry |
◆ Lysates | ||
AIMP1-578HCL | Recombinant Human AIMP1 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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