Recombinant Human CD4 Molecule(26-226aa)
Cat.No. : | CD4-103H |
Product Overview : | Recombinant Human CD-4 produced inEscherichia Coliencodes amino acids 26-226. |
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Cat. No. : | CD4-103H |
Description : | CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E-cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes. |
Source : | Escherichia Coli. |
Physical Appearance : | Sterile filtered liquid. |
Formulation : | Recombinant Human protein at 100µg/ml in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol. |
Application and Suggested Dilutions : | •ELISA •Inhibition Assays •Western Blotting |
Characterization : | On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kDa. |
Storage : | Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycle. |
Gene Name : | CD4 CD4 molecule [ Homo sapiens ] |
Synonyms : | CD4; CD4 molecule; CD4mut; T-cell surface glycoprotein CD4; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD antigen; CD4 antigen; CD4 receptor |
Gene ID : | 920 |
mRNA Refseq : | NM_000616 |
Protein Refseq : | NP_000607 |
MIM : | 186940 |
UniProt ID : | P01730 |
Chromosome Location : | 12pter-p12 |
Pathway : | Antigen processing and presentation; Cell adhesion molecules (CAMs); Hematopoietic cell lineage; Primary immunodeficiency; T cell receptor signaling pathway; HIV Infection; Signaling in Immune system |
Function : | MHC class II protein binding; coreceptor activity; extracellular matrix structural constituent; protein homodimerization activity; protein kinase binding; transmembrane receptor activity; zinc ion binding |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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