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Recombinant Human CD4 protein, His-Avi-tagged

Cat.No. : CD4-293H
Product Overview : Human CD40 is expressed from mammalian with a His and a Avi tag at the C-terminal. It contains Glu21-Arg193.
  • Specification
  • Gene Information
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Description : CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.
Source : HEK293
Species : Human
Tag : His-Avi
Form : Supplied as 0.22um filtered solution in PBS (pH 7.4).
Molecular Mass : The protein has a predicted MW of 22.1 kDa. Due to glycosylation, the protein migrates to 35-40 KDa based on Bis-Tris PAGE result.
Protein length : It contains Glu21-Arg193.
Endotoxin : Less than 0.1 EU per ug by the LAL method.
Purity : > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : CD4 CD4 molecule [ Homo sapiens ]
Official Symbol : CD4
Synonyms : CD40; CD40L receptor; TNFRSF5; B cell surface antigen CD40; B-cell surface antigen CD40; Bp50B cell-associated molecule; CD40 antigen; CD40 molecule, TNF receptor superfamily member 5; CD40 type II isoform; CDw40; MGC9013; nerve growth factor receptor-related B-lymphocyte activation molecule; p50; TNFRSF5CD40 antigen (TNF receptor superfamily member 5); tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5
Gene ID : 920
mRNA Refseq : NM_000616
Protein Refseq : NP_000607
MIM : 186940
UniProt ID : P01730

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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