"HBG1" Related Products

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Recombinant Human HBG1, His-tagged

Cat.No.: HBG1-7642H
Product Overview: Recombinant human HBG1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5" - epsilon– gamma-G – gamma-A –delta – beta - 3".
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol.
Molecular Mass: 18kDa (170aa)
Protein length: 1-147aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGHFTEE DKATITSLWG KVNVEDAGGE TLGRLLVVYP WTQRFFDSFG NLSSASAIMG NPKVKAHGKK VLTSLGDATK HLDDLKGTFA QLSELHCDKL HVDPENFKLL GNVLVTVLAI HFGKEFTPEV QASWQKMVTA VASALSSRYH
Purity: >85% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Concentration: 0.25mg/ml?
Gene Name: HBG1 hemoglobin, gamma A [ Homo sapiens ]
Official Symbol: HBG1
Synonyms: HBG1; hemoglobin, gamma A; hemoglobin subunit gamma-1; hb F Agamma; gamma globin; A-gamma globin; gamma-1-globin; gamma A hemoglobin; hemoglobin gamma-1 chain; hemoglobin gamma-a chain; hemoglobin, gamma, regulator of; HBGA; HBGR; HSGGL1; PRO2979;
Gene ID: 3047
mRNA Refseq: NM_000559
Protein Refseq: NP_000550
MIM: 142200
UniProt ID: P69891
Chromosome Location: 11p15.5
Function: heme binding; metal ion binding; oxygen binding; oxygen transporter activity;

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