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Recombinant Human KDM1A, His-GST tagged

Cat.No.: KDM1A-8606H
Product Overview: Recombinant Human KDM1A (O60341-1) (Ser172-Met852), fused with the N-terminal poly histidine-tagged GST tag, was produced in Baculovirus-Insect cells.
Source: Baculovirus-Insect Cells
Species: Human
Tag: His-GST
Form: Lyophilized from a 0.2μm filtered solution of 20mM Tris, 500mM NaCl, 2mM DTT, pH 8.0, 10% gly
Molecular Mass: The recombinant human KDM1 /GST chimera consists of 917 amino acids and has a calculated molecular mass of 103.3 kDa. The recombinant protein migrates as an approximately 93 kDa band in SDS-PAGE under reducing conditions.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: KDM1A lysine (K)-specific demethylase 1A [ Homo sapiens ]
Official Symbol: KDM1A
Synonyms: KDM1A; lysine (K)-specific demethylase 1A; amine oxidase (flavin containing) domain 2 , AOF2, KDM1, lysine (K) specific demethylase 1; lysine-specific histone demethylase 1A; BHC110; KIAA0601; LSD1; lysine (K)-specific demethylase 1; BRAF35-HDAC complex protein BHC110; lysine-specific histone demethylase 1; amine oxidase (flavin containing) domain 2; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; AOF2; KDM1;
Gene ID: 23028
mRNA Refseq: NM_001009999
Protein Refseq: NP_001009999
MIM: 609132
UniProt ID: O60341
Chromosome Location: 1p36.12
Pathway: Coregulation of Androgen receptor activity, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem;
Function: MRF binding; androgen receptor binding; chromatin binding; demethylase activity; enzyme binding; flavin adenine dinucleotide binding; histone demethylase activity; histone demethylase activity (H3-K4 specific); histone demethylase activity (H3-K9 specific); histone demethylase activity (H3-dimethyl-K4 specific); ligand-dependent nuclear receptor transcription coactivator activity; oxidoreductase activity; p53 binding; protein binding; transcription factor binding; transcription regulatory region DNA binding;

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