"ATP2C1" Related Products

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Recombinant Human ATP2C1, His-tagged

Cat.No.: ATP2C1-10012H
Product Overview: Recombinant Human ATP2C1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
Source: E.coli
Species: Human
Tag: His
Protein length: 320-654a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 [ Homo sapiens ]
Official Symbol: ATP2C1
Synonyms: ATP2C1; ATPase, Ca++ transporting, type 2C, member 1; BCPM, benign chronic pemphigus (Hailey Hailey disease); calcium-transporting ATPase type 2C member 1; ATP2C1A; KIAA1347; PMR1; secretory pathway Ca2+/Mn2+ ATPase 1; SPCA1; HUSSY-28; ATPase 2C1; ATPase, Ca(2+)-sequestering; ATP-dependent Ca(2+) pump PMR1; HHD; BCPM; hSPCA1;
Gene ID: 27032
mRNA Refseq: NM_001001485
Protein Refseq: NP_001001485
MIM: 604384
UniProt ID: P98194
Chromosome Location: 3q21.3
Pathway: Ion channel transport, organism-specific biosystem; Ion transport by P-type ATPases, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; calcium transport I, organism-specific biosystem;
Function: ATP binding; ATP binding; calcium ion binding; calcium-transporting ATPase activity; NOT calcium-transporting ATPase activity; calcium-transporting ATPase activity; calcium-transporting ATPase activity; hydrolase activity; hydrolase activity, acting on ac

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