Recombinant Human ATP2C1, His-tagged
Cat.No. : | ATP2C1-10012H |
Product Overview : | Recombinant Human ATP2C1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 320-654a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 [ Homo sapiens ] |
Official Symbol : | ATP2C1 |
Synonyms : | ATP2C1; ATPase, Ca++ transporting, type 2C, member 1; BCPM, benign chronic pemphigus (Hailey Hailey disease); calcium-transporting ATPase type 2C member 1; ATP2C1A; KIAA1347; PMR1; secretory pathway Ca2+/Mn2+ ATPase 1; SPCA1; HUSSY-28; ATPase 2C1; ATPase, Ca(2+)-sequestering; ATP-dependent Ca(2+) pump PMR1; HHD; BCPM; hSPCA1; |
Gene ID : | 27032 |
mRNA Refseq : | NM_001001485 |
Protein Refseq : | NP_001001485 |
MIM : | 604384 |
UniProt ID : | P98194 |
Chromosome Location : | 3q21.3 |
Pathway : | Ion channel transport, organism-specific biosystem; Ion transport by P-type ATPases, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; calcium transport I, organism-specific biosystem; |
Function : | ATP binding; ATP binding; calcium ion binding; calcium-transporting ATPase activity; NOT calcium-transporting ATPase activity; calcium-transporting ATPase activity; calcium-transporting ATPase activity; hydrolase activity; hydrolase activity, acting on ac |
Products Types
◆ Recombinant Protein | ||
ATP2C1-281R | Recombinant Rhesus Macaque ATP2C1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATP2C1-268H | Recombinant Human ATP2C1 Protein, His-tagged | +Inquiry |
ATP2C1-974H | Recombinant Human ATP2C1 protein, GST-tagged | +Inquiry |
ATP2C1-0816H | Recombinant Human ATP2C1 Protein (Met1-Pro70), N-GST tagged | +Inquiry |
ATP2C1-452R | Recombinant Rhesus monkey ATP2C1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ATP2C1-148HCL | Recombinant Human ATP2C1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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