Recombinant Human BECN1, GST-tagged

• Cat.No.: BECN1-10203H
• Product Overview: Recombinant Human BECN1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-310a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: BECN1 beclin 1, autophagy related [ Homo sapiens ]
• Official Symbol: BECN1
• Synonyms: BECN1; beclin 1, autophagy related; beclin 1 (coiled coil, moesin like BCL2 interacting protein); beclin-1; ATG6; ATG6 autophagy related 6 homolog (S. cerevisiae); VPS30; ATG6 autophagy related 6 homolog; coiled-coil myosin-like BCL2-interacting protein; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin1
• Gene ID: 8678
• mRNA Refseq: NM_003766
• Protein Refseq: NP_003757
• MIM: 604378
• UniProt ID: Q14457
• Chromosome Location: 17q21
• Pathway: Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem; Senescence and Autophagy, organism-specific biosystem
• Function: protein binding