Recombinant Human DHFR, GST-tagged
Cat.No. : | DHFR-11966H |
Product Overview : | Recombinant Human DHFR protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-187a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | DHFR dihydrofolate reductase [ Homo sapiens ] |
Official Symbol : | DHFR |
Synonyms : | DHFR; dihydrofolate reductase; DYR; DHFRP1; |
Gene ID : | 1719 |
mRNA Refseq : | NM_000791 |
Protein Refseq : | NP_000782 |
MIM : | 126060 |
UniProt ID : | P00374 |
Chromosome Location : | 5q11.2-q13.2 |
Pathway : | Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; E2F mediated regulation of DNA replication, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; |
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DHFR-2586H | Recombinant Human DHFR Protein, GST-tagged | +Inquiry |
DHFR-2354M | Recombinant Mouse DHFR Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
DHFR-6946HCL | Recombinant Human DHFR 293 Cell Lysate | +Inquiry |
DHFR-353HCL | Recombinant Human DHFR cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2100 | Dihydrofolate Reductase Inhibitor Screening Kit | +Inquiry |
Kit-2097 | Dihydrofolate Reductase Colorimetric Activity Kit | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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