Recombinant Human GFAP, His-tagged
Cat.No. : | GFAP-13227H |
Product Overview : | Recombinant Human GFAP protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 1-76a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol |
Gene Name : | GFAP glial fibrillary acidic protein [ Homo sapiens ] |
Official Symbol : | GFAP |
Synonyms : | GFAP; glial fibrillary acidic protein; FLJ45472; intermediate filament protein; FLJ42474; |
Gene ID : | 2670 |
mRNA Refseq : | NM_001131019 |
Protein Refseq : | NP_001124491 |
MIM : | 137780 |
UniProt ID : | P14136 |
Chromosome Location : | 17q21 |
Pathway : | Nuclear signaling by ERBB4, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by ERBB4, organism-specific biosystem; |
Function : | integrin binding; structural constituent of cytoskeleton; |
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GFAP-2164R | Recombinant Rat GFAP Protein, His (Fc)-Avi-tagged | +Inquiry |
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◆ Native Protein | ||
GFAP-171B | Native bovine GFAP | +Inquiry |
GFAP-18P | Native Porcine GFAP Protein | +Inquiry |
GFAP-526H | Native Human GFAP protein | +Inquiry |
◆ Lysates | ||
GFAP-5955HCL | Recombinant Human GFAP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGFAP is crucial for maintaining the structure and function of astrocytes in the CNS.
GFAP is used as a biomarker to assess astrocyte activation and neural damage.
It forms intermediate filaments, providing mechanical support and stability to astrocytes.
It plays a protective role, participating in the glial scar formation post-injury.
Dysregulation of GFAP can lead to impaired astrocyte function and neural dysfunction.
Increased GFAP levels are observed in gliosis, neurodegenerative diseases, and brain injuries.
Therapeutic interventions may aim at modulating GFAP expression to mitigate neural damage.
Customer Reviews (3)
Write a reviewFast, efficient customer service.
Product works great in assays.
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