Recombinant Human GGCX, GST-tagged

• Cat.No.: GGCX-13240H
• Product Overview: Recombinant Human GGCX protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 383-758a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GGCX gamma-glutamyl carboxylase [ Homo sapiens ]
• Official Symbol: GGCX
• Synonyms: GGCX; gamma-glutamyl carboxylase; vitamin K-dependent gamma-carboxylase; vitamin K dependent gamma carboxylase; VKCFD1; peptidyl-glutamate 4-carboxylase; FLJ26629
• Gene ID: 2677
• mRNA Refseq: NM_000821
• Protein Refseq: NP_000812
• MIM: 137167
• UniProt ID: P38435
• Chromosome Location: 2p12
• Pathway: Gamma-carboxylation of protein precursors, organism-specific biosystem; Gamma-carboxylation, transport, and amino-terminal cleavage of proteins, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, organism-specific biosystem; Post-translational protein modification, organism-specific biosystem
• Function: gamma-glutamyl carboxylase activity; lyase activity