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Recombinant Human GRB10, GST-tagged

Cat.No.: GRB10-13518H
Product Overview: Recombinant Human GRB10 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.
Source: E.coli
Species: Human
Tag: GST
Protein length: 1-80a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: GRB10 growth factor receptor-bound protein 10 [ Homo sapiens ]
Official Symbol: GRB10
Synonyms: GRB10; growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally expressed gene 1; insulin receptor-binding protein Grb-IR; RSS; IRBP; MEG1; GRB-IR; Grb-10; KIAA0207;
Gene ID: 2887
mRNA Refseq: NM_001001549
Protein Refseq: NP_001001549
MIM: 601523
UniProt ID: Q13322
Chromosome Location: 7p12.2
Pathway: EGFR1 Signaling Pathway, organism-specific biosystem; IGF1 pathway, organism-specific biosystem; Insulin Pathway, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem; Kit Receptor Signaling Pathway, organism-specific biosystem; PDGFR-beta signaling pathway, organism-specific biosystem;
Function: SH3/SH2 adaptor activity; insulin receptor binding; protein binding;

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