"IL15RA" Related Products

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Recombinant Human IL15RA, His-tagged

Cat.No.: IL15RA-14151H
Product Overview: Recombinant Human IL15RA protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Source: E.coli
Species: Human
Tag: His
Protein length: 1-231a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: IL15RA interleukin 15 receptor, alpha [ Homo sapiens ]
Official Symbol: IL15RA
Synonyms: IL15RA; interleukin 15 receptor, alpha; interleukin-15 receptor subunit alpha; CD215; IL 15RA; MGC104179;
Gene ID: 3601
mRNA Refseq: NM_001243539
Protein Refseq: NP_001230468
MIM: 601070
UniProt ID: Q13261
Chromosome Location: 10p15.1
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem;
Function: cytokine receptor activity; protein binding; receptor activity; signal transducer activity;

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