Recombinant Human GPX8, His-tagged

• Cat.No.: GPX8-96H
• Product Overview: Recombinant Human Probable Glutathione Peroxidase 8/GPX8 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Leu209) of Human GPX8 fused with a polyhistidine tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 1-209 a.a.
• Description: Probable Glutathione Peroxidase 8 (GPX8) is a member of the glutathione peroxidase family. GPX8 is a single-pass membrane protein and catalysis glutathione into glutathione disulfide. It is shown that GPX8 interacts with 17alpha-ethynylestradiol, diuron and 2-butoxyethanol (ortholog). In addition, GPX8 is involved in response to oxidative stress.
• AA Sequence: MEPLAAYPLKCSGPRAKVFAVLLSIVLCTVTLFLLQLKFLKPKINSFYAFEVKDAKGRTV SLEK YKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSK EVESFARK NYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKF WKPEEPIEVIRP DIAALVRQVIIKKKEDLVDHHHHHH
• Endotoxin: Less than 0.1 ng/μg (1 IEU/μg).
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

Gene Information

• Gene Name: GPX8 glutathione peroxidase 8 (putative) [ Homo sapiens ]
• Official Symbol: GPX8
• Synonyms: GPX8; glutathione peroxidase 8 (putative); probable glutathione peroxidase 8; EPLA847; UNQ847; GPx-8; GSHPx-8
• Gene ID: 493869
• mRNA Refseq: NM_001008397
• Protein Refseq: NP_001008398
• UniProt ID: Q8TED1
• Chromosome Location: 5q11.2
• Pathway: glutathione redox reactions I, organism-specific biosystem
• Function: glutathione peroxidase activity; oxidoreductase activity