||Recombinant Human Probable Glutathione Peroxidase 8/GPX8 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Leu209) of Human GPX8 fused with a polyhistidine tag at the C-terminus.
||Probable Glutathione Peroxidase 8 (GPX8) is a member of the glutathione peroxidase family. GPX8 is a single-pass membrane protein and catalysis glutathione into glutathione disulfide. It is shown that GPX8 interacts with 17alpha-ethynylestradiol, diuron and 2-butoxyethanol (ortholog). In addition, GPX8 is involved in response to oxidative stress.
||MEPLAAYPLKCSGPRAKVFAVLLSIVLCTVTLFLLQLKFLKPKINSFYAFEVKDAKGRTV SLEK YKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSK EVESFARK NYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKF WKPEEPIEVIRP DIAALVRQVIIKKKEDLVDHHHHHH
||Less than 0.1 ng/μg (1 IEU/μg).
||Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.