Recombinant Human FZD10, Fc-tagged

• Cat.No.: FZD10-283H
• Product Overview: A DNA sequence encoding the human FZD10 (NP_009128.1) (Met1-Gly161) was expressed with the Fc region of human IgG1 at the C-terminus.

Specification

• Source: Human Cells
• Species: Human
• Tag: Fc
• Form: Lyophilized from sterile PBS, pH7.4.
• Molecular Mass: The recombinant human FZD10/Fc comprises 379 amino acids and has a predicted molecular mass of 42.8 kDa. The apparent molecular mass of the protein is approximately 48.7 kDa in SDS-PAGE under reducing conditions.
• Protein length: Met1-Gly161
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >90 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: FZD10 frizzled family receptor 10 [ Homo sapiens ]
• Official Symbol: FZD10
• Synonyms: FZD10; frizzled family receptor 10; frizzled (Drosophila) homolog 10 , frizzled 10, seven transmembrane spanning receptor , frizzled homolog 10 (Drosophila); frizzled-10; CD350; frizzled homolog 10; frizzled 10, seven transmembrane spanning receptor; Fz10; FzE7; FZ-10; hFz10
• Gene ID: 11211
• mRNA Refseq: NM_007197
• Protein Refseq: NP_009128
• MIM: 606147
• UniProt ID: Q9ULW2
• Chromosome Location: 12q24.33
• Pathway: Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Melanogenesis, organism-specific biosystem
• Function: G-protein coupled receptor activity; PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding; protein binding; receptor activity; signal transducer activity