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Recombinant Mouse IL18, MIgG2a Fc-tagged, mutant

Cat.No.: IL18-638M
Product Overview: The extracellular domain of mouse IL-18 (NP_032386.1)(Asn36-Ser192) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a was expressed in CHO cell.
Description: The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity inspleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively splicedtranscript variants encoding different isoforms have been found for this gene
Source: CHO cell
Species: Mouse
Tag: MIgG2a Fc-tagged, mutant
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Induction of IFN-γ in response to the recombinant mouse IL-18 was measured.
Molecular Mass: 45KDa (monomer)
AA Sequence: Asn36-Ser192
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: Il18 interleukin 18 [ Mus musculus ]
Official Symbol: IL18
Synonyms: IL18; interleukin 18; interleukin-18; IL-1 gamma; interleukin-1 gamma; IFN-gamma-inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor; Igif; Il-18;
Gene ID: 16173
mRNA Refseq: NM_008360
Protein Refseq: NP_032386
Pathway: African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Hypertrophy Model, organism-specific biosystem;
Function: cytokine activity;

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