Recombinant Human IL18, MIgG2a Fc-tagged

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Recombinant Human IL18, MIgG2a Fc-tagged

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Cat.No. : IL18-546H
Product Overview : The extracellular domain of human IL-18 (NP_001553.1)(Tyr37-Asp193) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.
Description : The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : CHO cell
Species : Human
Tag : MIgG2a Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Induction of IFN-γ in response to the recombinant human IL-18 was measured using human IFN-γ ELISA.
Molecular Mass : 44KDa (monomer)
AA Sequence : Tyr37-Asp1 93
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : IL18 interleukin 18 (interferon-gamma-inducing factor) [ Homo sapiens ]
Official Symbol : IL18
Synonyms : IL18; interleukin 18 (interferon-gamma-inducing factor); interleukin-18; IGIF; IL 1g; IL 18; IL1F4; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; IL-18; IL-1g; MGC12320;
Gene ID : 3606
mRNA Refseq : NM_001243211
Protein Refseq : NP_001230140
MIM : 600953
UniProt ID : Q14116
Chromosome Location : 11q22.2-q22.3
Pathway : African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cellular roles of Anthrax toxin, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem;
Function : cytokine activity; cytokine activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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