Recombinant Mouse EGF, MIgG2a Fc-tagged

Cat.No.: EGF-316M
Product Overview: The extracellular domain of mouse EGF (AAH17681.1) (Asn960-Arg1012) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell
Description: This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as alarge precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factorpeptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferationand differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor,epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation ofthis gene has been associated with the growth and progression of certain cancers. Alternate splicing results inmultiple transcript variants
Source: CHO cellS
Species: Mouse
Tag: MIgG2a Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured in a cell proliferation assay.
Molecular Mass: 32KDa (monomer)
AA Sequence: Asn960-Arg1012
Endotoxin: <0.06 eu/μg as determined by lal>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: Egf epidermal growth factor [ Mus musculus ]
Official Symbol: EGF
Synonyms: EGF; epidermal growth factor; pro-epidermal growth factor; Pro-epidermal growth factor precursor (EGF); AI790464;
Gene ID: 13645
mRNA Refseq: NM_010113
Protein Refseq: NP_034243
Pathway: Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Disease, organism-specific biosystem; EGFR downregulation, organism-specific biosystem;
Function: calcium ion binding; epidermal growth factor receptor binding; epidermal growth factor receptor binding; growth factor activity; protein binding;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.