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Recombinant Human DAXX 293 Cell Lysate

Cat.No. : DAXX-7071HCL
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  • Gene Information
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Description : Antigen standard for death-domain associated protein (DAXX), transcript variant 2 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
Source : HEK 293 cells
Species : Human
Components : This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
Size : 0.1 mg
Storage Instruction : Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
Applications : ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.
Gene Name : DAXX death-domain associated protein [ Homo sapiens ]
Official Symbol : DAXX
Synonyms : DAXX; death-domain associated protein; death associated protein 6; death domain-associated protein 6; DAP6; Fas-binding protein; CENP-C binding protein; ETS1-associated protein 1; death-associated protein 6; fas death domain-associated protein; EAP1; BING2; MGC126245; MGC126246;
Gene ID : 1616
mRNA Refseq : NM_001141969
Protein Refseq : NP_001135441
MIM : 603186
UniProt ID : Q9UER7
Chromosome Location : 6p21.3
Pathway : Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; HIV-1 Nef: Negative effector of Fas and TNF-alpha, organism-specific biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; IL-6 Signaling Pathway, organism-specific biosystem;
Function : androgen receptor binding; enzyme binding; heat shock protein binding; p53 binding; protein N-terminus binding; protein binding; protein homodimerization activity; receptor signaling protein activity; transcription coactivator activity; transcription factor binding; ubiquitin protein ligase binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does DAXX protein interact with other cellular proteins in the context of clinical applications? 01/01/2023

DAXX protein interacts with a wide range of cellular proteins, including transcription factors, histones, and chromatin remodeling complexes, which has implications for its clinical relevance in various cellular processes.

What are the potential therapeutic implications of targeting DAXX protein? 09/03/2020

Targeting DAXX protein may have therapeutic implications in cancer treatment, as well as in aging-related diseases and neurodegenerative disorders, by modulating its functions and interactions with other cellular proteins.

Are there any clinical implications of DAXX protein in aging-related diseases? 02/22/2019

Studies have suggested that DAXX protein may have implications in aging-related diseases, particularly in relation to telomere dysfunction and cellular senescence.

How does DAXX protein contribute to the development of neurodegenerative diseases? 10/22/2017

DAXX protein has been implicated in neurodegenerative diseases through its involvement in cellular stress responses and protein aggregation, which are hallmarks of diseases such as Alzheimer's and Parkinson's.

Can DAXX protein be used as a therapeutic target for cancer treatment? 07/30/2016

DAXX protein has been identified as a potential therapeutic target for cancer treatment due to its involvement in regulating the activity of key oncogenes and tumor suppressor genes.

Customer Reviews (3)

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Reviews
01/29/2021

    Its ability to provide accurate and reliable results in this particular application makes it a preferred choice for researchers studying antigen-antibody interactions and immune responses.

    09/27/2019

      The DAXX protein's sensitivity and specificity ensure precise measurements, contributing to the overall success of ELISA experiments.

      10/26/2018

        the DAXX protein has proven to be invaluable in protein electron microscopy structure analysis.

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