Recombinant Human CNTF cell lysate

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Recombinant Human CNTF cell lysate

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Cat.No. : CNTF-376HCL
Description : The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : CNTF ciliary neurotrophic factor [ Homo sapiens ]
Official Symbol : CNTF
Synonyms : CNTF; ciliary neurotrophic factor; HCNTF;
Gene ID : 1270
mRNA Refseq : NM_000614
Protein Refseq : NP_000605
MIM : 118945
UniProt ID : P26441
Chromosome Location : 11q12
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function : ciliary neurotrophic factor receptor binding; cytokine activity; growth factor activity; interleukin-6 receptor binding;

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