Recombinant Human ESRRA cell lysate

• Cat.No.: ESRRA-576HCL

Specification

• Description: The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: ESRRA estrogen-related receptor alpha [ Homo sapiens ]
• Official Symbol: ESRRA
• Synonyms: ESRRA; estrogen-related receptor alpha; ESRL1; steroid hormone receptor ERR1; ERR1; ERRa; ERRalpha; NR3B1; ERR-alpha; estrogen receptor-like 1; estrogen-related nuclear receptor alpha; nuclear receptor subfamily 3 group B member 1
• Gene ID: 2101
• mRNA Refseq: NM_004451
• Protein Refseq: NP_004442
• MIM: 601998
• UniProt ID: P11474
• Chromosome Location: 11q12
• Pathway: Energy Metabolism, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Mitochondrial Gene Expression, organism-specific biosystem
• Function: DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; protein domain specific binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding