Recombinant Human PAK2 cell lysate

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Recombinant Human PAK2 cell lysate

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Cat.No. : PAK2-1276HCL
Description : The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 [ Homo sapiens ]
Official Symbol : PAK2
Synonyms : PAK2; p21 protein (Cdc42/Rac)-activated kinase 2; p21 (CDKN1A) activated kinase 2; serine/threonine-protein kinase PAK 2; PAK65; PAKgamma; S6/H4 kinase; p58; PAK-2; gamma-PAK; p21-activated kinase 2; p21 (CDKN1A)-activated kinase 2;
Gene ID : 5062
mRNA Refseq : NM_002577
Protein Refseq : NP_002568
MIM : 605022
UniProt ID : Q13177
Chromosome Location : 3q29
Pathway : Activation of Rac, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem;
Function : ATP binding; identical protein binding; nucleotide binding; protein binding; protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; protein tyrosine kinase activator activity;

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