Recombinant Human JAM2, Fc-tagged
Cat.No. : | JAM2-174H |
Product Overview : | Recombinant Human JAM2 /CD322 Protein, With C-Fc Tag (rh JAM2 / CD322 Fc Chimera) Phe 29 - Asn 236 (Accession # AAH17779) was produced in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Junctional adhesion molecule B (JAM-B) is also known as Junctional adhesion molecule 2 (JAM-2), Vascular endothelial junction-associated molecule (VE-JAM), CD antigen CD322, which belongs to the immunoglobulin superfamily. JAM-B contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. JAM-B is highest expression in the heart, placenta, lung, foreskin and lymph node. JAM-B may play a role in the processes of lymphocyte homing to secondary lymphoid organs. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Molecular Mass : | rh JAM2 / CD322 Fc Chimera is fused with human IgG1 Fc tag at the C-terminus, and has a calculated MW of 50 kDa. The predicted N-terminus is Phe 29. DTT-reduced Protein migrates as 60-68 kDa in SDS-PAGE due to glycosylation. |
Endotoxin : | Less than 1.0 EU per μg of the rh JAM2 / CD322 Fc Chimera by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC). |
Reconstitution : | See Certificate of Analysis for reconstitution instructions and specific concentrations. |
Gene Name : | JAM2 junctional adhesion molecule 2 [ Homo sapiens ] |
Official Symbol : | JAM2 |
Synonyms : | JAM2; junctional adhesion molecule 2; C21orf43; junctional adhesion molecule B; CD322; JAM B; JAMB; VE JAM; JAM-2; JAM-IT/VE-JAM; vascular endothelial junction-associated molecule; JAM-B; VEJAM; PRO245; VE-JAM; |
Gene ID : | 58494 |
mRNA Refseq : | NM_021219 |
Protein Refseq : | NP_067042 |
MIM : | 606870 |
UniProt ID : | P57087 |
Chromosome Location : | 21q21.2 |
Pathway : | Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, conserved biosystem; Hemostasis, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem; |
Function : | protein binding; protein heterodimerization activity; |
Products Types
◆ Recombinant Protein | ||
Jam2-789M | Recombinant Mouse Jam2 protein(Met1-Asn236), His-tagged | +Inquiry |
JAM2-3187H | Recombinant Human JAM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
JAM2-1428H | Recombinant Human JAM2 Protein (29-238 aa), His-tagged | +Inquiry |
Jam2-1706R | Recombinant Rat Jam2 Protein, His-tagged | +Inquiry |
JAM2-1735R | Recombinant Rhesus Monkey JAM2 Protein, hIgG1-tagged | +Inquiry |
◆ Lysates | ||
JAM2-2123MCL | Recombinant Mouse JAM2 cell lysate | +Inquiry |
JAM2-1399RCL | Recombinant Rat JAM2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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