"PDE1C" Related Products

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Recombinant Human PDE1C, GST-tagged

Cat.No. : PDE1C-1612H
Product Overview : Full-length recombinant human PDE1C was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex.
Source : Sf9 insect cells
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 445 nmol/min/mg
Molecular Mass : ~99 kDa
Protein length : Full Length
Purity : >90%
Applications : PDE Assay
Stability : 1 yr at -70oC from date of shipment.
Storage : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 ug/ul
Gene Name : PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa [ Homo sapiens ]
Official Symbol : PDE1C
Synonyms : PDE1C; phosphodiesterase 1C, calmodulin-dependent 70kDa; phosphodiesterase 1C, calmodulin dependent (70kD); calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1C; Hcam3; hCam-3; cam-PDE 1C; Human 3,5 cyclic nucleotide phosphodiesterase (HSPDE1C1A)
Gene ID : 5137
mRNA Refseq : NM_005020
Protein Refseq : NP_005011
MIM : 602987
UniProt ID : Q14123
Chromosome Location : 7p14.3
Pathway : Ca-dependent events; Calmodulin induced events; DAP12 interactions
Function : calmodulin binding; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; metal ion binding

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