Recombinant Human Aryl hydrocarbon receptor LBD/Hsp90 complex, GST-tagged AHR-109H

Recombinant Human Aryl hydrocarbon receptor LBD/Hsp90 complex, GST-tagged

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Recombinant Human Aryl hydrocarbon receptor LBD/Hsp90 complex, GST-tagged

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Cat.No. : AHR-109H
Product Overview : Recombinant Human GST-tagged Aryl hydrocarbon receptor ligand-binding domain (AhR-LBD) consists of a 218 a.a. GST tag, a 16 a.a. flexible linker and a 207 a.a. Aryl hydrocarbon receptor ligand binding domain, Acc# NP_001612.1, amino acids 231-437. Human Aryl hydrocarbon receptor ligand-binding domain in complex with human Hsp90 was produced in insect cells co-infected with two recombinant baculoviruses. GST tagged AhR-LBD and Hsp90 are the major components of the complex.
Description : In the cytoplasm Aryl hydrocarbon receptor is found in complex with Hsp90. Complex of Aryl hydrocarbon receptor with Hsp90 is essential for ligand-dependent activation of the receptor.
Source : Sf9 insect cells
Species : Human
Tag : GST
Form : 20 mM Na-P pH 8.0, 40 mM KCl, 20 mM Na2MoO4, 7 mM reduced glutathione, 15% glycerol.
Purity : >80%
Applications : Development of Ligand binding and coactivator peptide recruitment assays.
Storage : Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.
Publication :
Gene Name : AHR aryl hydrocarbon receptor [ Homo sapiens ]
Official Symbol : AHR
Synonyms : AHR; aryl hydrocarbon receptor; bHLHe76; AH-receptor; ah receptor; aromatic hydrocarbon receptor; class E basic helix-loop-helix protein 76;
Gene ID : 196
mRNA Refseq : NM_001621
Protein Refseq : NP_001612
MIM : 600253
UniProt ID : P35869
Chromosome Location : 7p15
Pathway : Adipogenesis, organism-specific biosystem;
Function : DNA binding; DNA binding; Hsp90 protein binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; protein binding; protein dimerization activity; protein heterodimerization activity; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; signal transducer activity; transcription factor binding; transcription regulatory region DNA binding;

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