Recombinant Human ESRRA, GST-tagged

• Cat.No.: ESRRA-123H
• Product Overview: Recombinant Human GST-tagged Estrogen-related receptor alpha ligand-binding domain (ESRRA-LBD) consists of a 218 a.a. GST tag, a 13 a.a. flexible linker and a 244 a.a. ESRRA-LBD, Acc# AAH92470.1, amino acids 180-423, was expressed in baculovirus-infected insect cells and purified using affinity chromatography.

Specification

• Description: Estrogen-related receptor alpha (ERR-α or ESRRA) is also known as NR3B1 (nuclear receptor subfamily 3, group B, member 1).
• Source: Sf9 insect cells
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 0.5 mM EDTA, 3 mM Dithiothreitol, 7 mM reduced glutathione, 20% glycerol.
• Purity: >90%
• Applications: Ligand binding and coactivator peptide recruitment assays.
• Storage: Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.

Gene Information

• Gene Name: ESRRA estrogen-related receptor alpha [ Homo sapiens ]
• Official Symbol: ESRRA
• Synonyms: ESRRA; estrogen-related receptor alpha; ESRL1; steroid hormone receptor ERR1; ERR1; ERRa; ERRalpha; NR3B1; ERR-alpha; estrogen receptor-like 1; estrogen-related nuclear receptor alpha; nuclear receptor subfamily 3 group B member 1
• Gene ID: 2101
• mRNA Refseq: NM_004451
• Protein Refseq: NP_004442
• MIM: 601998
• UniProt ID: P11474
• Chromosome Location: 11q12
• Pathway: Energy Metabolism, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Mitochondrial Gene Expression, organism-specific biosystem
• Function: DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; protein domain specific binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding