"IGHG3" Related Products


Native Human Immunoglobulin G3 (IgG3)

Cat.No.: IGHG3-231H
Description: Like IgG1, IgG3 activates complement and has an affinity for fc receptors; thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection.
Source: Human Plasma
Species: Human
Form: Liquid
Molecular Mass: MW: 170,000
Purity: >=95% by SDS-PAGE.
Usage: For research use only.
Quality Control Test: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Stability: >1 year
Storage: +2 to 6°C; Do NOT Freeze
Storage Buffer: 20 mM phosphate, pH 7.4, with 150 mM NaCl and 0.05% NaN3.
Gene Name: IGHG3 Immunoglobulin heavy constant gamma 3(G3m marker) [ Homo sapiens ]
Official Symbol: IGHG3
Synonyms: IGHG3; Immunoglobulin heavy constant gamma 3(G3m marker);
Gene ID: 3502
Chromosome Location: 14q32.33
Pathway: Classical antibody-mediated complement activation, organism-specific biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem
Function: antigen binding

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