Recombinant Human CTTN, GST-tagged
Cat.No. : | CTTN-27H |
Product Overview : | Recombinant Human CTTN ( 1 a.a. - 513 a.a.), fused with GST-tag at N-terminal, was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 83.9 kDa |
AA Sequence : | MWKASAGHAVSIAQDDAGADDWETD PDFVNDVSEKEQRWGAKTVQGSGHQ EHINIHKLRENVFQEHQTLKEKELE TGPKASHGYGGKFGVEQDRMDKSAV GHEYQSKLSKHCSQVDSVRGFGGKF GVQMDRVDQSAVGFEYQGKTEKHAS QKDYSSGFGGKYGVQADRVDKSAVG FDYQGKTEKHESQRDYSKGFGGKYG IDKDKVDKSAVGFEYQGKTEKHESQ KDYVKGFGGKFGVQTDRQDKCALGW DHQEKLQLHESQKDYSKGFGGKYGV QKDRMDKNASTFEDVTQVSSAYQKT VPVEAVTSKTSNIRANFENLAKEKE QEDRRKAEAERAQRMAKERQEQEEA RRKLEEQARAKTQTPPVSPAPQPTE ERLPSSPVYEDAASFKAELSYRGPV SGTEPEPVYSMEAADYREASSQQGL AYATEAVYESAEAPGHYPAEDSTYD EYENDLGITAVALYDYQAAGDDEIS FDPDDIITNIEMIDDGWWRGVCKGR YGLFPANYVELRQ |
Applications : | ELISA; WB-Re; AP; Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CTTN cortactin [ Homo sapiens (human) ] |
Official Symbol : | CTTN |
Synonyms : | CTTN; cortactin; EMS1, ems1 sequence (mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); src substrate cortactin |
Gene ID : | 2017 |
mRNA Refseq : | NM_138565 |
Protein Refseq : | NP_612632 |
MIM : | 164765 |
UniProt ID : | Q14247 |
Chromosome Location : | 11q13 |
Pathway : | Bacterial invasion of epithelial cells; FGF signaling pathway; Pathogenic Escherichia coli infection |
Function : | protein binding |
Products Types
◆ Recombinant Protein | ||
CTTN-915R | Recombinant Rhesus Macaque CTTN Protein, His (Fc)-Avi-tagged | +Inquiry |
Cttn-431M | Recombinant Mouse Cttn Protein, His-tagged | +Inquiry |
Cttn-432R | Recombinant Rat Cttn Protein, His-tagged | +Inquiry |
CTTN-1330R | Recombinant Rat CTTN Protein, His (Fc)-Avi-tagged | +Inquiry |
CTTN-782H | Recombinant Human CTTN Protein, DDK-tagged | +Inquiry |
◆ Lysates | ||
CTTN-421HCL | Recombinant Human CTTN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, CTTN protein interacts with various signaling pathways involved in cancer progression, including those regulating cell migration and invasion.
CTTN protein expression can be evaluated using immunohistochemistry on tumor tissue samples obtained from patients.
Yes, CTTN protein has been implicated in neurological disorders such as Alzheimer's disease, and its role in these conditions is also being investigated.
Yes, CTTN protein is involved in various cellular processes such as cell adhesion, migration, and cytoskeletal dynamics.
CTTN protein expression can be regulated by various factors, including oncogenes, tumor suppressor genes, and signaling pathways involved in cancer development.
Customer Reviews (3)
Write a reviewIts high quality, coupled with the manufacturer's exceptional technical support, make it a reliable and effective choice for addressing my scientific inquiries.
This has greatly facilitated my experimental workflow, ensuring a readily available and dependable protein source whenever I need it.
I confidently recommend the CTTN protein to any researcher seeking a superior protein that not only fulfills their experimental needs but is also backed by unparalleled support from the manufacturer.
Ask a Question for All CTTN Products
Required fields are marked with *
My Review for All CTTN Products
Required fields are marked with *
Inquiry Basket