Recombinant Human GZMM, His-tagged GZMM-98H

Recombinant Human GZMM, His-tagged

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Recombinant Human GZMM, His-tagged

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Cat.No. : GZMM-98H
Product Overview : Recombinant Human GZMM(Ile26~Ala257), fused with N-terminal His-Tag, was expressed in E.coli.
Description : This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in reproduction and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein (proPACAP) and pro-insulin-like growth factor II.
Source : E.coli
Species : Human
Tag : His
Form : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Molecular Mass : 25.6kDa
AA Sequence : The target protein is fused with N-terminal His-Tag, its sequence is listed below.MGHHHHHHSGSEF-IIGGR EVIPHSRPYM ASLQRNGSHL CGGVLVHPKW VLTAAHCLAQ RMAQLRLVLG LHTLDSPGLT FHIKAAIQHP RYKPVPALEN DLALLQLDGK VKPSRTIRPL ALPSKRQVVA AGTRCSMAGW GLTHQGGRLS RVLRELDLQV LDTRMCNNSR FWNGSLSPSM VCLAADSKDQ APCKGDSGGP LVCGKGRVLA RVLSFSSRVC TDIFKPPVAT AVAPYVSWIR KVTGRSA
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : SDS-PAGE; WB; ELISA; IP.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : GZMM granzyme M (lymphocyte met-ase 1) [ Homo sapiens (human) ]
Official Symbol : GZMM
Synonyms : GZMM; granzyme M (lymphocyte met-ase 1); granzyme M; LMET1; lymphocyte met ase 1; MET1; met-ase; HU-Met-1; lymphocyte met-ase 1; Met-1 serine protease; natural killer cell granular protease
Gene ID : 3004
mRNA Refseq : NM_005317
Protein Refseq : NP_005308
MIM : 600311
UniProt ID : P51124
Chromosome Location : 19p13.3
Pathway : Alternative complement activation; Complement cascade; Initial triggering of complement
Function : serine-type endopeptidase activity; serine-type peptidase activity

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