Recombinant Human TXNDC12, His-tagged
Cat.No. : | TXNDC12-3498H |
Product Overview : | Recombinant Human TXNDC12(His 27 - Leu 172), fused with 6×His tag at the C-terminus, was expressed in human 293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Molecular Mass : | rhTXNDC12, fused with 6×His tag at the C-terminus, has a calculated MW of 17.3 kDa. The predicted N-terminus is His 27. DTT-reduced Protein migrates as 18-21 kDa. |
Endotoxin : | Less than 1.0 EU per μg of the rhTXNDC12 by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at:In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) [ Homo sapiens (human) ] |
Official Symbol : | TXNDC12 |
Synonyms : | TXNDC12; thioredoxin domain containing 12 (endoplasmic reticulum); thioredoxin domain-containing protein 12; AGR1; anterior gradient homolog 1 (Xenopus laevis); endoplasmic reticulum thioredoxin superfamily member; 18 kDa; ERP18; ERP19; hAG 1; PDIA16; protein disulfide isomerase family A; member 16; TLP19; ER protein 18; ER protein 19; anterior gradient homolog 1; thioredoxin-like protein p19; endoplasmic reticulum protein ERp19; endoplasmic reticulum resident protein 18; endoplasmic reticulum resident protein 19; protein disulfide isomerase family A, member 16; endoplasmic reticulum thioredoxin superfamily member, 18 kDa; AG1; ERP16; hAG-1; hTLP19 |
Gene ID : | 51060 |
mRNA Refseq : | NM_015913 |
Protein Refseq : | NP_056997 |
MIM : | 609448 |
UniProt ID : | O95881 |
Chromosome Location : | 1p32.3 |
Pathway : | Glutathione metabolism |
Function : | protein binding; protein-disulfide reductase (glutathione) activity |
Products Types
◆ Recombinant Protein | ||
TXNDC12-1870M | Recombinant Mouse TXNDC12 Protein (25-170 aa), His-tagged | +Inquiry |
Txndc12-6746M | Recombinant Mouse Txndc12 Protein, Myc/DDK-tagged | +Inquiry |
TXNDC12-6029R | Recombinant Rat TXNDC12 Protein, His (Fc)-Avi-tagged | +Inquiry |
TXNDC12-4850R | Recombinant Rhesus Macaque TXNDC12 Protein, His (Fc)-Avi-tagged | +Inquiry |
TXNDC12-1925M | Recombinant Mouse TXNDC12 Protein (25-170 aa), His-tagged | +Inquiry |
◆ Lysates | ||
TXNDC12-626HCL | Recombinant Human TXNDC12 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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