Active Recombinant Mouse Ntn1

• Cat.No.: Ntn1-255M
• Product Overview: Recombinant Mouse Ntn1 (Accession # AAC52971) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Mouse
• Predicted N Terminal: Val22
• Form: Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
• Bio-activity: Measured by its binding ability in a functional ELISA.Immobilized rrUNC5H2/Fc Chimera at 5 µg/mL (100 µL/well) can bind rmNetrin-1 with a linear range of 3-200 ng/mL.
• Molecular Mass: Recombinant Mouse Ntn1 has a calculated MW of 68.2 kDa. In SDS-PAGE migrates as 83 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: Ntn1 netrin 1 [ Mus musculus ]
• Official Symbol: Ntn1
• Synonyms: NTN1; netrin 1; netrin-1; AI561871; BC019633; Netrin-1
• Gene ID: 18208
• mRNA Refseq: NM_008744
• Protein Refseq: NP_032770

Reviews

04/26/2022

It has high biological activity, high clearance rate and high safety.

02/03/2021

The storage conditions are broad and do not affect the activity of the protein,

01/27/2019

This protein is very reproducible.

Q&As

Are there have any use of NTN1 protein in cancer immunotherapy?

The targeted effect of NTN1 protein can be used to develop tumor immunotherapy drugs for the immune recognition and killing mechanism of tumors.

What are the applications of NTN1 protein in restorative and regenerative medicine?

NTN1 protein can help with cell migration, proliferation, and directed growth, so it may be a potential therapeutic target for cell therapy and restorative medicine.

In which diseases does NTN1 protein play an important role?

NTN1 protein not only plays an important role in the development of the nervous system, but also closely related to the occurrence and development of various diseases such as nervous system tumors, cardiovascular diseases and inflammatory diseases.

Is the NTN1 protein associated with inflammation?

Yes, NTN1 protein is involved in the regulatory process of inflammatory response and may play an important role in the occurrence and development of inflammatory diseases.

What is the role of NTN1 protein in autoimmune diseases?

This protein is closely related to the occurrence and progression of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus, and may be involved in the regulation of autoimmune responses.

Why does NTN1 protein play a role in transplantation immunity?

NTN1 protein may be involved in the regulation of graft rejection, affecting immune tolerance and treatment efficacy after transplantation. It is also a potential transplant immunotherapy target.