Active Recombinant Mouse Ldlr Protein, His-tagged
Cat.No. : | Ldlr-646M |
Product Overview : | Recombinant Mouse Ldlr (Accession # NP_034830) Ala22-Arg790, fused with a C-terminal 10-His tag, was produced in Mouse myeloma cell line, NS0-derived. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian cells |
Species : | Mouse |
Tag : | His |
Predicted N Terminal : | Ala22 |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein. |
Bio-activity : | Measured by its ability to bind immobilized human LDL in a functional ELISA. |
Molecular Mass : | Recombinant Mouse Ldlr, His-tagged has a calculated MW of 85.7 kDa. In SDS-PAGE migrates as 130-135 kDa, reducing conditions. |
Protein length : | Ala22-Arg790 |
Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Reconstitution : | Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Gene Name : | Ldlr low density lipoprotein receptor [ Mus musculus ] |
Official Symbol : | Ldlr |
Synonyms : | LDLR; low density lipoprotein receptor; low-density lipoprotein receptor; LDL receptor; Hlb301; |
Gene ID : | 16835 |
mRNA Refseq : | NM_001252658 |
Protein Refseq : | NP_001239587 |
MIM : |
Products Types
◆ Recombinant Protein | ||
LDLR-3027R | Recombinant Rat LDLR Protein, His (Fc)-Avi-tagged | +Inquiry |
LDLR-344H | Recombinant Human LDLR Protein, His-tagged | +Inquiry |
LDLR-422H | Recombinant Human LDLR Protein, MYC/DDK-tagged | +Inquiry |
Ldlr-5024M | Recombinant Mouse Ldlr Protein, His (Fc)-Avi-tagged | +Inquiry |
Ldlr-349M | Recombinant Mouse Ldlr Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
LDLR-85H | Native Human Lipoprotein | +Inquiry |
◆ Lysates | ||
LDLR-2780HCL | Recombinant Human LDLR cell lysate | +Inquiry |
LDLR-2762MCL | Recombinant Mouse LDLR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (5)
Ask a questionYes, conditions where increasing the expression or function of LDLR could potentially aid in reducing circulating LDL cholesterol and minimizing cardiovascular risk.
Yes, research is continually conducted to better understand LDLR-related conditions and to develop more effective treatments, including gene-editing technologies and novel therapies.
Dysfunction in LDLR can lead to high levels of LDL cholesterol in the blood, contributing to conditions like familial hypercholesterolemia and an increased risk of heart disease.
A dysfunctional LDLR can lead to an accumulation of LDL cholesterol in the arteries, promoting atherosclerosis, the hardening and narrowing of arteries.
Treatments involve lifestyle changes, cholesterol-lowering medications, and in some cases, gene therapies or specialized medications targeting the LDL receptor.
Customer Reviews (3)
Write a reviewThe LDLR protein stands out for its exceptional quality, making it an excellent choice to meet my experimental requirements.
Its purity and consistency guarantee reliable and reproducible results, ensuring the reliability of my research outcomes.
the LDLR protein offers superior quality and reliability, making it a perfect fit for my experimental needs.
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