"IL18RAP" Related Products

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Recombinant Human IL18RAP Protein, Fc Chimera

Cat.No.: IL18RAP-1073H
Product Overview: Recombinant Human IL18RAP (Accession # O95256), fused with , was produced in Mouse myeloma cell line, NS0-derived.
Source: NSO Cells
Species: Human
Tag: Fc
Predicted N Terminal: Phe20
Form: Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity: Measured by its ability to inhibit the IL-18-induced response of KG-1 human acute myelogenous leukemia cells in the presence of soluble Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera.The ED50 for this effect is typically 2 - 6 µg/mL in the presence of 30 µg/mL of soluble IL-18 R alpha/Fc and 40 ng/mL of human IL-18.
Molecular Mass: Recombinant Human IL18RAP, Fc Chimera has a calculated MW of 65.1 kDa (monomer). In SDS-PAGE migrates as 90-100 kDa, reducing conditions.
Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution: Reconstitute at 100 µg/mL 4 mM HCl containing at least 0.1% human or bovine serum albumin.
Gene Name: IL18RAP interleukin 18 receptor accessory protein [ Homo sapiens ]
Official Symbol: IL18RAP
Synonyms: IL18RAP; interleukin 18 receptor accessory protein; interleukin-18 receptor accessory protein; AcPL; CD218b; IL-1R7; IL-1R-7; IL-18RAcP; IL-1RAcPL; IL-18Rbeta; IL-18R-beta; IL-18 receptor beta; interleukin-1 receptor 7; interleukin-18 receptor beta; IL-18 receptor accessory protein; CD218 antigen-like family member B; ACPL; IL18RB; CDw218b; MGC120589; MGC120590;
Gene ID: 8807
mRNA Refseq: NM_003853
Protein Refseq: NP_003844
MIM: 604509
UniProt ID: O95256
Chromosome Location: 2q12.1

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