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Recombinant Human S100 Calcium Binding Protein A9

Cat. No.: S100A9-433H
Product Overview: Recombinant Human S100 Calcium Binding Protein A9 cloned from human cDNA, was expressed inE.coli. The protein consists of the human S100A9 (residues 1-114) with a mutation at position 3: Cys3Ser. MW = 13.2 kDa.
Description: Protein S100-A9 is a protein that in humans is encoded by the S100A9 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis.
Source: E.Coli.
Purity: > 95% by SDS-PAGE. The protein was observed as a single band migrating at a molecular weight of (<20 kDa).
Supplied As: 0.5 mg at 1 mg/ml in Tris-HCl 10mM, NaCl 100mM pH 7.5 CaCl2 1mM. The concentration is calculated from the absorbance at 280nm (e280 = 6990M-1cm-1).
Characteristics: Under the above described conditions, to avoid precipitation or protein dimerization, the product can be concentrated to a maximum 1mM.
Storage: -20º C. The protein is stable at 4 ºC for at least 3 days and at 25 ºC for at least several hours. After initial defrost, aliquot product into individual tubes and refreeze at -20º C. Avoid repeated freeze/defrost cycles.
Gene Name: S100A9 S100 calcium binding protein A9 [ Homo sapiens ]
Synonyms: S100A9; S100 calcium binding protein A9; MIF; NIF; P14; CAGB; CFAG; CGLB; L1AG; LIAG;MRP14; 60B8AG; MAC387; S100A9; S100; MRP-14 calcium-binding protein A9 (calgranulin B); S100 calcium binding protein A9 (calgranulin B); calgranulin B; OTTHUMP00000015331; Calprotectin L1H subunit; Leukocyte L1 complex heavy chain
Gene ID: 6280
mRNA Refseq: NM_002965
Protein Refseq: NP_002956
MIM: 123886
UniProt ID: P06702
Chromosome Location: 1q21
Function: calcium ion binding; protein binding; signal transducer activity

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