Recombinant Human Profilin 1

• Cat.No.: PFN1-1401H
• Product Overview: Recombinant Human Profilin1 protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 15.0 kDa (140aa).

Specification

• Cat. No.: PFN1-1401H
• Description: Profilin1 is a ubiquitous actin monomer-binding protein belonging to the profilin family. This protein significantly enhances skin wound healing in-vitro and in-vivo that may be mediated by purinergic receptors. It is also active in endothelial cell migration and vessel sprouting. It is thought to regulate actin polymerization in response to extracellular signals.
• Source: E.coli.
• Amino Acid Sequence: MAGWNAYIDN LMADGTCQDA AIVGYKDSPS VWAAVPGKTF VNITPAEVGV LVGKDRSSFY VNGLTLGGQK CSVIRDSLLQ DGEFSMDLRT KSTGGAPTFN VTVTKTDKTL VLLMGKEGVH GGLINKKCYE MASHLRRSQY
• Form: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol.
• Purity: > 95% by SDS – PAGE.
• Concentration: 1.0 mg/ml (determined by Bradford assay).
• Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PFN1 profilin 1 [ Homo sapiens ]
• Synonyms: PFN1; profilin 1; Profilin-1; Profilin I
• Gene ID: 5216
• mRNA Refseq: NM_005022
• Protein Refseq: NP_005013
• MIM: 176610
• UniProt ID: P07737
• Chromosome Location: 17p13.2
• Pathway: Regulation of actin cytoskeleton
• Function: Rho GTPase binding; actin binding; proline-rich region binding