Recombinant Human CDC-like Kinase 1, GST-tagged, Active CLK1-284H

Recombinant Human CDC-like Kinase 1, GST-tagged, Active

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Recombinant Human CDC-like Kinase 1, GST-tagged, Active

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Cat. No. : CLK1-284H
Product Overview : Recombinant human CLK1 (129-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=66 kDa.
Description : CLK/STY is a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. The phosphorylated serine/arginine-rich (SR) proteins involves in the pre-mRNA processing and releasing through nucleus into nucleoplasm. CLK/STY, which could phosphorylates the specific SR proteins, such as ASF/SF2, may directly regulates the activity and compartmentalization of SR splicing factors.
Source : Sf9 insect cellsusing baculovirus.
Sequence : 129-end.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
PDB rendering based on 1z57. :

Gene Name : CLK1 CDC-like kinase 1 [ Homo sapiens ]
Synonyms : CLK1; CDC-like kinase 1; CLK; STY; CLK/STY; CDC28/CDC2-like kinase; protein tyrosine kinase STY; dual specificity protein kinase CLK1; EC 2.7.12.1
Gene ID : 1195
mRNA Refseq : NM_001162407
Protein Refseq : NP_001155879
MIM : 601951
UniProt ID : P49759
Chromosome Location : 2q33
Function : ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein serine/threonine kinase activity; transferase activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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