"CLK1" Related Products

Recombinant Human CDC-like Kinase 1, GST-tagged, Active

Cat. No. : CLK1-284H
Product Overview : Recombinant human CLK1 (129-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=66 kDa.
Description : CLK/STY is a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. The phosphorylated serine/arginine-rich (SR) proteins involves in the pre-mRNA processing and releasing through nucleus into nucleoplasm. CLK/STY, which could phosphorylates the specific SR proteins, such as ASF/SF2, may directly regulates the activity and compartmentalization of SR splicing factors.
Source : Sf9 insect cellsusing baculovirus.
Sequence : 129-end.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : CLK1 CDC-like kinase 1 [ Homo sapiens ]
Synonyms : CLK1; CDC-like kinase 1; CLK; STY; CLK/STY; CDC28/CDC2-like kinase; protein tyrosine kinase STY; dual specificity protein kinase CLK1; EC 2.7.12.1
Gene ID : 1195
mRNA Refseq : NM_001162407
Protein Refseq : NP_001155879
MIM : 601951
UniProt ID : P49759
Chromosome Location : 2q33
Function : ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein serine/threonine kinase activity; transferase activity

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