Recombinant Human CDC-like Kinase 1, GST-tagged, Active
Cat.No. : | CLK1-284H |
Product Overview : | Recombinant human CLK1 (129-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=66 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CLK1-284H |
Description : | CLK/STY is a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. The phosphorylated serine/arginine-rich (SR) proteins involves in the pre-mRNA processing and releasing through nucleus into nucleoplasm. CLK/STY, which could phosphorylates the specific SR proteins, such as ASF/SF2, may directly regulates the activity and compartmentalization of SR splicing factors. |
Source : | Sf9 insect cellsusing baculovirus. |
Sequence : | 129-end. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | CLK1 CDC-like kinase 1 [ Homo sapiens ] |
Synonyms : | CLK1; CDC-like kinase 1; CLK; STY; CLK/STY; CDC28/CDC2-like kinase; protein tyrosine kinase STY; dual specificity protein kinase CLK1; EC 2.7.12.1 |
Gene ID : | 1195 |
mRNA Refseq : | NM_001162407 |
Protein Refseq : | NP_001155879 |
MIM : | 601951 |
UniProt ID : | P49759 |
Chromosome Location : | 2q33 |
Function : | ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein serine/threonine kinase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
CLK1-1490H | Active Recombinant Human CLK1 Protein, GST-His-tagged | +Inquiry |
CLK1-1759M | Recombinant Mouse CLK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLK1-737R | Recombinant Rhesus Macaque CLK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLK1-2688H | Recombinant Human CLK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLK1-1491H | Recombinant Human CLK1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
CLK1-7441HCL | Recombinant Human CLK1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1571 | CLK1 Kinase Binding Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionCLK1 expression is tightly regulated at transcriptional and post-translational levels, ensuring its proper function in normal cellular processes.
Researchers often measure CLK1 activity through in vitro kinase assays or by monitoring its phosphorylation targets in cellular or tissue samples.
Yes, studies suggest that CLK1 inhibitors may have therapeutic potential for neurodegenerative disorders by modulating RNA splicing.
Some studies suggest that CLK1 mutations may be associated with certain diseases, but further research is needed to establish clear links.
Yes, several CLK1 inhibitors are in preclinical and clinical development as potential anticancer agents.
Customer Reviews (3)
Write a reviewThe manufacturer's commitment to customer satisfaction extends beyond technical support. They offer a comprehensive range of related products and resources to aid researchers in their trials.
From troubleshooting to optimizing experimental protocols, the manufacturer provides diligent support to ensure the success of the trial.
The CLK1 protein offers several advantageous features that make it an ideal choice for researchers conducting trials.
Ask a Question for All CLK1 Products
Required fields are marked with *
My Review for All CLK1 Products
Required fields are marked with *
Inquiry Basket