Recombinant Human PTPRS, GST-tagged, Active

• Cat.No.: PTPRS-470H
• Product Overview: Recombinant human PTPRS (883-1201) was expressed inE.Coliusing an N-terminal GST tag. MW=63kDa.

Specification

• Cat. No.: PTPRS-470H
• Description: PTPRS is a member of a subfamily of receptor type PTPases that is characterized by the presence of an extracellular cell adhesion molecule-like motif and 2 intracellular phosphatase domains. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis.
• Source: E.Coli.
• Sequence: 883-1201.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• 22q13.33: 19p13.3

Gene Information

• Gene Name: PTPRS protein tyrosine phosphatase, receptor type, S [ Homo sapiens ]
• Synonyms: PTPRS; protein tyrosine phosphatase, receptor type, S; PTPSIGMA; protein tyrosine phosphatase, receptor type, sigma; protein tyrosine phosphatase PTPsigma; EC 3.1.3.48
• Gene ID: 5802
• mRNA Refseq: NM_002850
• Protein Refseq: NP_002841
• MIM: 601576
• UniProt ID: Q13332
• Function: heparan sulfate proteoglycan binding; heparin binding; hydrolase activit; protein binding; protein kinase binding; transmembrane receptor protein tyrosine phosphatase activity