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Recombinant Human LOXL4

Cat.No.: LOXL4-28220TH
Product Overview: Recombinant fragment, corresponding to amino acids 500-756 of Human LOXL4 expressed in a baculovirus-infected Sf9 cell expression system; 257 amino acids, MWt 31kDa.
Description: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Form: Liquid
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Gene Name: LOXL4 lysyl oxidase-like 4 [ Homo sapiens ]
Official Symbol: LOXL4
Synonyms: LOXL4; lysyl oxidase-like 4; lysyl oxidase homolog 4; FLJ21889; LOXC;
Gene ID: 84171
mRNA Refseq: NM_032211
Protein Refseq: NP_115587
MIM: 607318
Uniprot ID: Q96JB6
Chromosome Location: 10q24
Function: copper ion binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; protein binding;

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