"IL1RAP" Related Products


Recombinant Human Interleukin 1 Receptor Accessory Protein-Like 1

Cat. No. : IL1RAP-1638H
Description : IL-1R accessory protein (IL-1RAcP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. IL-1RAcP is an indispensible molecule in the IL-1 receptor signal transduction complex, necessary to link events on the plasma membrane level to downstream signaling pathways, allowing IL-1-dependent activation of transcription factors and gene expression. IL-1R AcP represents a novel target for blocking IL-1 function in human disease.
Source : Sf 21 Insect Cells.
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Molecular Weight : The predicted molecular weight of Recombinant Human IL-1 R3 is Mr 67.4 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-75 kDa.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Gene Name : L1RAP interleukin 1 receptor accessory protein [ Homo sapiens ]
Synonyms : IL1RAP; interleukin 1 receptor accessory protein; IL1R3; C3orf13; FLJ37788; IL-1RAcP; OTTHUMP00000209486; OTTHUMP00000209487; OTTHUMP00000209489; OTTHUMP00000209492; interleukin-1 receptor accessory protein beta; IL-1 receptor accessory protein; IL-1RAcP
Gene ID : 3556
mRNA Refseq : NM_002182
Protein Refseq : NP_002173
MIM : 602626
UniProt ID : Q9NPH3
Chromosome Location : 3q28
Pathway : Apoptosis; Cytokine-cytokine receptor interaction
Function : interleukin-1 receptor activity; protein binding; transmembrane receptor activity

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