Recombinant Human MAP4K1
Cat.No. : | MAP4K1-27602TH |
Product Overview : | Recombinant fragment corresponding to amino acids 1-346 of Human MAP4K1 with an N terminal proprietary tag, MWt 65 kDa. |
- Specification
- Gene Information
- Related Products
Description : | Mitogen-activated protein kinase kinase kinase kinase 1 is a protein kinase that in humans is encoded by the MAP4K1 gene.. It is also known as HPK1 (Hematopoietic Progenitor Kinase 1). |
Protein length : | 346 amino acids |
Molecular Weight : | 65.000kDa inclusive of tags |
Source : | Baculovirus infected sf9 cells |
Tissue specificity : | Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine. |
Biological activity : | The Specific activity of MAP4K1-27602TH was determined to be 125 nmol/min/mg. |
Form : | Liquid |
Purity : | by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.Contains 1 CNH domain.Contains 1 protein kinase domain. |
Gene Name : | MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 [ Homo sapiens ] |
Official Symbol : | MAP4K1 |
Synonyms : | MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1; hematopoietic progenitor kinase 1; HPK1; |
Gene ID : | 11184 |
mRNA Refseq : | NM_001042600 |
Protein Refseq : | NP_001036065 |
MIM : | 601983 |
Uniprot ID : | Q92918 |
Chromosome Location : | 19q13.1-q13.4 |
Pathway : | B Cell Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; JNK signaling in the CD4+ TCR pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; |
Function : | ATP binding; MAP kinase kinase kinase kinase activity; nucleotide binding; protein binding; protein kinase activity; |
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MAP4K1-03M | Recombinant Monkey MAP4K1 Protein, C-His tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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