Cat. No.:	IL4R-1645H
Description:	Human IL-4 exerts its biological effects via signaling through its receptor system, IL-4R. There are two types of the IL-4 receptor complexes, the type I receptor consisting of the IL-4R alpha and the common gamma chain, yc and the type II receptor consisting of IL-4R alpha and the IL-13R alpha. The IL-4R alpha chain contains an extracellular domain of 207 amino acids, a transmembrane domain of 24 amino acids, and an intracellular domain of 569 amino acids.
Source:	NSO Cells.
State Of Matter:	Lyophilized.
Purity:	>95% by SDS Page and analyzed by silver stain.
Endotoxin:	<0.1 ng per 1 µg as determined by the LAL method.
Molecular Weight:	The predicted molecular weight of Recombinant Human IL-4 R is Mr 50.5 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 75-85 kDa.
Storage And Stability:	This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Gene Name:	IL4R interleukin 4 receptor [ Homo sapiens ]
Synonyms:	IL4R; interleukin 4 receptor; CD124; IL4RA; interleukin 4 receptor alpha chain; OTTHUMP00000122506; interleukin-4 receptor alpha chain; CD_antigen; IL-4R-alpha; Soluble interleukin-4 receptor alpha chain; sIL4Ralpha/prot; IL-4-binding protein; IL4-BP
Gene ID:	3566
mRNA Refseq:	NM_000418
Protein Refseq:	NP_000409
MIM:	147781
UniProt ID:	P24394
Chromosome Location:	16p12.1-p11.2
Pathway:	Cytokine-cytokine receptor interaction; Endocytosis; Hematopoietic cell lineage; Jak-STAT signaling pathway
Function:	interleukin-4 receptor activity; receptor activity; protein binding; receptor signaling protein activity

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