Cat. No.: |
IL4R-1645H |
Description: |
Human IL-4 exerts its biological effects via signaling through its receptor system, IL-4R. There are two types of the IL-4 receptor complexes, the type I receptor consisting of the IL-4R alpha and the common gamma chain, yc and the type II receptor consisting of IL-4R alpha and the IL-13R alpha. The IL-4R alpha chain contains an extracellular domain of 207 amino acids, a transmembrane domain of 24 amino acids, and an intracellular domain of 569 amino acids. |
Source: |
NSO Cells. |
State Of Matter: |
Lyophilized. |
Purity: |
>95% by SDS Page and analyzed by silver stain. |
Endotoxin: |
<0.1 ng per 1 µg as determined by the LAL method. |
Molecular Weight: |
The predicted molecular weight of Recombinant Human IL-4 R is Mr 50.5 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 75-85 kDa. |
Storage And Stability: |
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |