Recombinant Pig IL4R Protein (33-240 aa), His-sumostar-tagged
|Product Overview :||Recombinant Pig IL4R Protein (33-240 aa) is produced by Yeast expression system. This protein is fused with a 6xHis-sumostar tag at the N-terminal. Research Area: Cancer. Protein Description: Partial.|
- Gene Information
- Related Products
|Description :||Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.|
|Form :||Tris-based buffer,50% glycerol|
|Molecular Mass :||40.2 kDa|
|Protein length :||33-240 aa|
|AA Sequence :||VRVLEWPICLSDYVSTSTCEWRMAG PVNCSAEFRLSYQLKFFNTENHTTC VPENRAGSVCVCHMLMESIVIVDTY QLDLWAGEQLLWNSSFKPSQNVKPL APRNLMVHANISHTWLLTWSNPYPS ESYLYSELTYLVNISNENDPTDFRI YNVTYLGPTLRFPANTLKSGAAYSA RVKAWAQRYNSTWSEWSPSVKWLNY YEEPLEQR|
|Purity :||> 85% as determined by SDS-PAGE.|
|Notes :||Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.|
|Storage :||The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.|
|Concentration :||A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.|
|Gene Name :||IL4R interleukin 4 receptor [ Sus scrofa ]|
|Official Symbol :||IL4R|
|Synonyms :||IL4R; interleukin 4 receptor; interleukin-4 receptor subunit alpha; IL-4RA; IL-4R-alpha; IL-4R subunit alpha;|
|Gene ID :||397614|
|mRNA Refseq :||NM_214340|
|Protein Refseq :||NP_999505|
|UniProt ID :||Q863Z5|
|◆ Recombinant Protein|
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|IL4R-2388P||Recombinant Pig IL4R Protein (33-240 aa), His-tagged||+Inquiry|
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|IL4R-4443H||Recombinant Human IL4R Protein, His (Fc)-Avi-tagged||+Inquiry|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
IL4R is a synthetic protein that mimics the IL-4 signaling pathway in nature and binds to the IL-4 receptor in cells, which can be used to study the IL-4 signaling pathway and related diseases.
Common IL4R production technologies include prokaryotic expression systems and mammalian cell expression systems.
This protein is used in tumor immunotherapy, which can promote anti-tumor immune response and enhance the anti-tumor effect of cytotoxic T lymphocytes.
It is mainly used in immunology, drug research and other fields. It is also widely used in vaccines, biotechnology, cancer treatment and so on.
IL4R is used to treat severe pheochromocytome-induced aerodoritis and was approved by the FDA as the first drug to treat this disease.
IL4R cannot generally be administered orally, and needs to be administered by injection or intravenous drip.
Customer Reviews (3)Write a review
Easy to attach to the surface of cells or materials. -
It has growth factor activity to promote cell growth and proliferation. -
In animals or humans caused by the prone production of antibodies. -
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