Recombinant Human MUC7

• Cat.No.: MUC7-28540TH
• Product Overview: Recombinant fragment of Human MUC7 with N terminal proprietary tag, 41kDa.

Specification

• Description: This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5 UTR, but encoding the same protein, have been found for this gene.
• Molecular Weight: 41.000kDa
• Source: E. coli
• Tissue specificity: Expressed in salivary gland tissues and only in those that contain mucous acinar cells (e.g. sublingual and submandibular glands) and not in salivary glands containing only serous acinar cells (e.g. parotid gland).
• Form: Lyophilised:Add 100ul of distilled water.
• Storage buffer: pH: 6.80Constituents:1.58% Tris HCl, 3.09% DTT, 4% SDS, 0.2% Bromophenol blue, 20% Sucrose
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Gene Information

• Gene Name: MUC7 mucin 7, secreted [ Homo sapiens ]
• Official Symbol: MUC7
• Synonyms: MUC7; mucin 7, secreted; mucin 7, salivary; mucin-7; FLJ27047; MG2
• Gene ID: 4589
• mRNA Refseq: NM_001145006
• Protein Refseq: NP_001138478
• MIM: 158375
• Uniprot ID: Q8TAX7
• Chromosome Location: 4q13.3
• Pathway: Salivary secretion, organism-specific biosystem; Salivary secretion, conserved biosystem
• Function: protein binding